Research Associate, HSC Reprogramming

We are hiring a new member of the HSC Therapeutics team who will be involved in making iPSC-derived HSCs, characterizing them, and developing them into a cellular therapy product. In this role, you will enable the HSC team to move faster and iterate more quickly by increasing the capacity for hands-on work in the lab. You will report to the HSC Lead.

About you:

You are great at prioritization within your work, allowing for efficient completion of tasks. You enjoy hands-on work and value being organized, planning, and paying attention to the details. You’re a highly collaborative team member with a “can-do” attitude and great communication skills.

In this role, you will:

• Perform regular culture of mammalian cells, mainly stable cell lines and iPSCs using aseptic tissue culture techniques.
• Assist with differentiating iPSC lines: prepare media, characterize differentiations using flow cytometry, perform media exchanges.
• Perform cell-based and molecular assays to characterize the cells and prove function (e.g. measuring gene expression with ddPCR, DNA and RNA extraction for NGS analysis).
• Assist in processing mouse tissues and performing flow cytometry to characterize cells.
• Work collaboratively across Retro teams such as Technical In-Vivo, Computational Biology, Automation, Quality and Analytics.
• Maintain an electronic lab notebook and contribute to supporting documents, such as SOPs.
• Ensure we have all the reagents we need: maintain stocks, aliquoting cytokines, tracking usage and delivery.

You might thrive in this role if you:

• Have a B.S in Biology or related field and at least 3 years of relevant experience or an M.S. with at least 1 year of post-degree research experience in industry.
• Learn/uptake information quickly and can follow established protocols.
• Have experience with standard tissue culture and mouse tissue processing techniques.
• Find joy in helping others and working with people with different technical backgrounds.
• Have excellent time management and prioritization skills.
• Are highly organized, energetic, detail-oriented, intellectually curious, ambitious, and deeply pragmatic.
• Thrive in a culture that embraces rapid iteration and open, straightforward and direct communication.

It’s a bonus if you:

• Have experience with bioreactor systems.
• Understanding of developmental hematopoiesis.
• Have experience working with iPSCs.

$85,000 – $110,000 a year
Total compensation also includes generous equity and benefits including:

– Medical, dental, and vision insurance for you and your family
– 401(k) plan with 4% matching
– Flexible time off and 10 company holidays per year
– Annual learning & development stipend
– Daily Retro-sponsored lunch and snacks