Associate Scientist Analytical Development

Vacancy Name Associate Scientist Analytical Development

Vacancy No VN665
Employment Type Permanent
Location of role Oxford, UK
Department CMC

Key Responsibilities As Associate Scientist Analytical Development, you will contribute to developing analytical methods to support Immunocore’s expanding pipeline of biopharmaceuticals. The core focus will be development and transfer of chromatography and electrophoresis-based methods for lot release and stability testing of protein products. Working closely with experienced scientists and cross-functional teams, you’ll contribute to study reports and operating procedures, drive continuous improvement, and expand your technical expertise in a dynamic, collaborative environment.

KEY RESPONSIBILITIES

• Running pre-established experimental investigations, with guidance from line managers, a mentor or colleagues.
• Developing and qualifying (ultra) high performance liquid chromatography (UHPLC), gel / capillary electrophoresis that support stability, lot release and characterisation testing as part of biopharmaceutical product development.
• Supporting process development by testing process intermediates and performing investigations.
• Contributing to the writing of operating procedures and study reports.
• Priorities: working to agreed experimental priorities and deadlines; raising issues or concerns with managers or colleagues so that these can be addressed.
• Technical knowledge: actively developing own knowledge, drawing on the experience of others and self-learning.
• Laboratory records: Ensuring that all records and data are up to date, on time and recorded to the correct standard, checking with a mentor or colleagues if unsure.
• Laboratory equipment: attending training on the use of technical instruments, using equipment appropriately, correctly and tidily.
• Health & Safety: compliance with all H&S requirements, attending appropriate training programmes

PERSON SPECIFICATION

Experience & knowledge

Essential
• A background in recombinant protein or antibody/biopharmaceutical analytical development or QC, with one or more years’ experience gained in industry.
• Hands on expertise of HPLC/UHPLC (e.g. size exclusion, ion exchange, reverse phase, hydrophobic interaction) for analysis of proteins.
• Hands on expertise of electrophoretic (e.g. CE-SDS) methods for analysis of proteins.
• Recorded results and information in a concise, accurate and timely way
• Learned about new practices through observation, self-learning and an enquiring mind
• Worked and contributed actively in a diverse team environment.

Desirable
• Experience of imaging capillary IEF (icIEF), Western blotting
• Knowledge of GMP
• Experience of lab organisation/maintenance
• Proactive in ensuring high quality of their work and seeking additional responsibilities to help meeting the goals of the team
• Familiar with principles of assay qualification/ validation i.e. robustness and suitability

Education & qualifications

• BSc. Or MSc. in biochemistry, biotechnology or related discipline