R&D Project Manager (F/M/X)

MISSIONS:

Your responsibilities include, but are not limited to:

Project planning and management:

• Write and structure scientific projects in a clear and well-argued manner;
• Develop detailed study schedules integrating the planned experiments and deadlines, taking into account internalized and/or externalized achievements;
• Participate in the definition, monitoring and optimization of the project budget by ensuring effective resource management;
• Participate in the identification and selection by mobilizing the necessary external resources (academic collaborations, CROs, industrial partners);
• Develop experimental protocols, in collaboration with internal teams and/or external partners;
• Write or supervise the writing of the synopsis of each study (primary, secondary objectives and associated evaluation criteria).

Execution of studies:

• Coordinate all aspects of studies, from design to sample collection and data analysis;
• Ensure smooth communication with management and other departments (regulatory, intellectual property, etc.) to guarantee the strategic alignment of the project;
• Master the experimental models used and surround yourself with appropriate experts if necessary;
• Identify and implement appropriate mitigation strategies in the event of technical or strategic difficulties;
• Interpret the results obtained in a cutting-edge and controlled scientific context while integrating strategic issues.

Scientific monitoring and documentation:

• Ensure relevant and continuous scientific monitoring, relying on the monitoring unit and mastering the scientific literature of the project;
• Promote innovation by proposing new scientific, technological or methodological approaches to maximize the impact of the project;
• Maintain comprehensive documentation of study activities, including study protocols, reports, and communicate study progress and results to stakeholders;
• Write or supervise the writing of abstracts, scientific publications and participate in the writing of patents when relevant.

Collaboration:

• Work closely with cross-functional teams, including other scientists, researchers, engineers and technicians, to ensure the successful execution of studies.

PROFILE :

• You hold a PhD or Master’s degree in biology, pharmacology, biomedical sciences or a related field, and you have a minimum of 3 years’ experience in scientific research or pharmacology;
• You have acquired expertise in one of the following themes:

-Pathophysiology: in-depth knowledge of pathophysiological mechanisms, particularly in hepatic pathophysiology, is an asset;
-Molecular mechanisms of action: you master the biological processes linked to tissue and cellular dysregulation, as well as the different forms of cell death (necroptosis, ferroptosis, apoptosis, etc.);
-Inflammation and immunopathology: you have a solid understanding of inflammatory and immune mechanisms;
-Preclinical pharmacology (including early ADME concepts/innovative therapeutics);

• You are proficient in experimental techniques in molecular and cellular biology: cell culture, western blot, ELISA, cytometry, immunohistochemistry, qPCR, OMICS tests, etc.
• You are also comfortable with murine animal models and experimental procedures;
• You are recognized for your ability to critically analyze experimental results and propose strategic adjustments;
• You also know how to propose innovative ideas and challenge existing approaches and working hypotheses to maximize the impact of scientific projects;
• You have excellent team spirit and know how to collaborate effectively with a variety of internal and external contacts, whether scientific, operational, or managerial;
• You demonstrate excellent organizational skills and know how to manage demanding deadlines with adaptability and flexibility;
• Your constructive stance allows you to facilitate discussions and bring about collective decisions;
• Your agile approach allows you to adapt quickly to new scientific data, developments in the field and operational constraints;
• You are proficient in office tools (Excel, PowerPoint, Word), biological data analysis software (GraphPad Prism, R, etc.), as well as project management tools;
• You communicate with ease, both orally and in writing, in French and English (minimum level C1).