Scientist, In Vivo / Cell Biology

What You Will Contribute To Altos

To understand the molecular, cellular, and metabolic mechanisms associated with transient cellular reprogramming, the mechanistic basis of cellular rejuvenation, and decipher the mechanism of cellular and tissue aging, focusing on skeletal muscle as a model system.

A great opportunity is available for Scientists to join Altos Labs in the Pura Muñoz-Canoves Lab at the San Diego Institute of Science (San Diego, CA). We seek highly motivated, skillful, and teamwork individuals who are passionate and dedicated to using their wet lab expertise to contribute to unraveling the deep basic biological mechanisms underlying cell health and resilience, including basic science and preclinical programs. Specifically, someone with expertise in in vivo mouse work and familiar with cell and tissue metabolism, and with biochemistry and protein-related benchwork experience will be greatly valued.

The successful candidate will collaborate with internal and external experimental groups, lead or participate in planning experimental designs, author and contribute to biological and methodological manuscripts, and contribute to seminars and other scientific initiations within Altos and a broader scientific community. Develop project-specific experimental strategies, techniques, and procedures. Carry out research projects in collaboration with the PI and senior scientists. Your work will lead to the generation of public knowledge in the form of publications; intellectual property in the form of patents; and will directly shape Altos’ pre-clinical programs. Responsibilities

Who You Are

We are open to candidates with a range of experience, as the position can be filled at the Scientist I or Scientist II level. The level of the position will depend on the qualifications of the selected candidate. Minimum requirements for the Scientist role include:

• Ph.D. and a documented record of professional achievement in the form of high-impact publications.
• Extensive experience in in vivo mouse work.
• At least 3 years of hands-on experience in protein Biochemistry and metabolic/metabolome studies
• Hands-on experience in cellular reprogramming
• Excellent computer and data mining skills.
• Problem-solving skills are sufficient to identify issues, research, and develop innovative solutions.
• Ability to maintain cooperative working relationships with a broad range of people, including staff colleagues, lab members, faculty, outside agencies and collaborators, and the community.
• Established high productivity and ability to complete work on time.
• Ability to organize work and set priorities.
• Ability to focus on details to produce accurate, quality work driven by deadlines.
• Ability to work in a dynamic environment and with others in a team.
• Strengths in dealing with ambiguity.

Preferred Qualifications

Candidates with previous experience and solid training in the following fields are favoured:

• Hands-on experience in cellular reprogramming in vitro or in vivo.
• Hands-on experience in protein biochemistry and metabolic/metabolome studies
• Molecular biology techniques, including recombinant viral vectors.
• Prior experience with animal handling, including disease models, is a plus.
• Comprehensive and solid experience in general molecular biology and cell culture techniques are required for this role.

The salary range for San Diego, CA

Scientist I: $116,450 – $157,550
Scientist II: $137,000 – $184,800
Exact compensation may vary based on skills, experience, and location.